Shape transitions in anisotropic multicomponent lipid tubules

Abstract Ternary mixtures of saturated and unsaturated lipids together with cholesterol can be induced to phase separate by photo-peroxidation into lipid-ordered Lo and lipid-disordered Ld domains.Because these have different mechanical properties, the phase separation is accompanied by dramatic changes in morphology.This work considers a tubule co

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Synthetic Versus Tissue-Engineered Implants for Joint Replacement

Human synovial joints are remarkable as they can last for a lifetime.However, they can be affected by disease that may lead to destruction of the joint surface.The most common treatment in the advanced stages of joint disease is artificial AEG DEK431010M SurroundCook Built-in Double Oven with Programmable Timer joint replacement, where the diseased

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Degradation of hexosylceramides is required for timely corpse clearance via formation of cargo-containing phagolysosomal vesicles

Efficient degradation of phagocytic cargo in lysosomes is crucial to maintain cellular homeostasis and defending cells against pathogens.However, the mechanisms underlying the degradation and recycling of macromolecular cargo Ottoman within the phagolysosome remain incompletely understood.We previously reported that the phagolysosome containing the

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